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Image Search Results
Journal: Scientific Reports
Article Title: Cytokeratin 7 expression as a predictor of an unfavorable prognosis in colorectal carcinoma
doi: 10.1038/s41598-021-97480-4
Figure Lengend Snippet: Histological images (magnification 200x) showing: ( A ) diffusely strongly CK7 + adenocarcinoma with a weak focal CK20 staining regarded as CK20- tumor; ( B ) diffusely strongly CK7 + and CK20- adenocarcinoma of cecum infiltrating CK7-/CK20 + non-neoplastic mucosa; ( C ) tumor budding cells with strong CK7 + /CK20 + ; ( D ) adenocarcinoma showing moderate CK7 + in ca 20% of cells and CK20 + in ca 80% of cells; ( E ) adenocarcinoma with CK7 expression in isolated single cells (< 1%), and weak CK20 staining in ca 40% of cells, regarded as CK7-/CK20 + . The hematoxylin eosin images document glandular arrangement of colorectal adenocarcinoma, in line c with tumor budding.
Article Snippet: Concerning immunohistochemistry, 4 µm-thick tissue sections were stained using a Ventana BenchMark ULTRA autostainer (Ventana Medical Systems, Tucson, Arizona) using monoclonal antibodies directed against
Techniques: Staining, Expressing, Isolation
Journal: Scientific Reports
Article Title: Cytokeratin 7 expression as a predictor of an unfavorable prognosis in colorectal carcinoma
doi: 10.1038/s41598-021-97480-4
Figure Lengend Snippet: Summarizing of the distribution of CRCs according the cytokeratin profile and all studied variables; including p values of X-square test.
Article Snippet: Concerning immunohistochemistry, 4 µm-thick tissue sections were stained using a Ventana BenchMark ULTRA autostainer (Ventana Medical Systems, Tucson, Arizona) using monoclonal antibodies directed against
Techniques:
Journal: Scientific Reports
Article Title: Cytokeratin 7 expression as a predictor of an unfavorable prognosis in colorectal carcinoma
doi: 10.1038/s41598-021-97480-4
Figure Lengend Snippet: Bar chart from univariate logistic regression showing a ratio of low/high grade ( A ), right/left sided tumors ( B ) and I + II/III + IV UICC stage cases ( C ) among CK7 ± , CK20 ± and MMR-proficient/deficient CRCs. CK7 + CRCs are insignificantly more high-grade and right-sided. CK20 + CRCs are significantly more left-sided. MMR deficient CRCs are significantly more frequently high-grade, right-sided and low-stage.
Article Snippet: Concerning immunohistochemistry, 4 µm-thick tissue sections were stained using a Ventana BenchMark ULTRA autostainer (Ventana Medical Systems, Tucson, Arizona) using monoclonal antibodies directed against
Techniques:
Journal: Scientific Reports
Article Title: Cytokeratin 7 expression as a predictor of an unfavorable prognosis in colorectal carcinoma
doi: 10.1038/s41598-021-97480-4
Figure Lengend Snippet: Kaplan Meier curves documenting CSS analysis concerning several selected variables. All death are showed in ( A ). There is a significantly worse survival in proximally situated tumors ( B ), advanced stage tumors ( C ), MMR-proficient tumors ( H ), CK7 + tumors using positivity cut-off on 10% ( E ) as well as on 1% ( F ). Using higher cut-off, the P -value is lower despite lower number of CK7 + cases (see discussion). Histopathological grade ( D ) is borderline insignificant despite visible trend in the curves. CK20 status ( G ) has no influence on survival.
Article Snippet: Concerning immunohistochemistry, 4 µm-thick tissue sections were stained using a Ventana BenchMark ULTRA autostainer (Ventana Medical Systems, Tucson, Arizona) using monoclonal antibodies directed against
Techniques: